Musical powerhouse Jason Isbell leads the pack in 2018's list of Americana Awards nominees, with nominations in four separate categories, stemming from his performances with his backing band, the 400 Unit, which includes his wife -- also a talented solo artist in her own right -- Amanda Shires. Margo Price and up-and-coming star Brandi Carlile follow close behind Isbell, with three nominations each.

The nominees were announced on Tuesday (May 15) during a special event broadcasted live from the Ford Theater at the Country Music Hall of Fame in Nashville, Tenn. The event was hosted by the Milk Carton Kids' Kenneth Pattengale and Joey Ryan, and included onstage appearances from nominees Molly Tuttle, Brittany Haas, Jerry Pentecost and Daniel Donato, along with other special guests.

The Americana Honors & Awards Ceremony will be held on September 12 at Nashville's Ryman Auditorium, as a part of the 2018 Americana Festival and Conference, which is set to take place from Sept.11-16. Brandy Clark, American Aquarium, Lee Ann Womack and more artists are set to perform during the festival. The winners will be revealed during that event, along with the recipient of the Americana Music Association's annual lifetime achievement award. Read on for a full list of nominees.

2018 Americana Music Awards Nominees

Album of the Year

All American Made, Margo Price (produced by Jeremy Ivey, Alex Munoz, Margot Price and Matt Ross-Spang)
By the Way, I Forgive You, Brandi Carlile (produced by Dave Cobb and Shooter Jennings)
The Nashville Sound, Jason Isbell & the 400 Unit (produced by Dave Cobb)
Rifles and Rosary Beads, Mary Gauthier (produced by Neilson Hubbard)

Artist of the Year

Brandi Carlile
Jason Isbell
Margo Price
John Prine

Song of the Year

"A Little Pain," Margo Price (written by Price)
"All the Trouble," LeeAnn Womack (written by Womack, Waylon Payne and Adam Wright)
"If We Were Vampires," Jason Isbell & the 400 Unit (written by Isbell)
"The Joke," Brandi Carlile (written by Carlile, Dave Cobb, Phil Hanseroth and Tim Hanseroth)

Duo/Group of the Year

I'm With Her
Jason Isbell & the 400 Unit
Lukas Nelson & the Promise of Real
Nathaniel Rateliff & the Night Sweats

Instrumentalist of the Year

Daniel Donato
Brittany Haas
Jerry Pentecost
Molly Tuttle

Emerging Artist of the Year

Courtney Marie Andrews
Tyler Childers
Anderson East
Lilly Hiatt

See Pictures From the 2017 Americana Music Awards